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McGraw Lab

Cross-species approaches to understand epilepsy & neurodevelopmental disorders and to identify novel treatments

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Our Research.

Animal models of epilepsy and neurodevelopmental disorders

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High-throughput chemical and genetic screens for novel therapy

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Genetics of human epilepsy

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Learning Healthcare Systems to improve outcomes in patients with epilepsy

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Publications.

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Uridine-responsive epileptic encephalopathy due to inherited variants in CAD: A Tale of Two Siblings

Credit: PubMed.gov

Uridine-responsive epileptic encephalopathy due to inherited variants in CAD: A Tale of Two Siblings

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News.

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Cristina Baker joins the McGraw research group!

Credit: Broad Institute

Dr. McGraw awarded CDKL5 Program of Excellence Pilot Grant award to model CDD in zebrafish!

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About Us.

Dr. Chris McGraw, MD, PhD

Dr. McGraw is an Adult Epileptologist at Massachusetts General Hospital on the Epilepsy Service and the Herscot Center for Tuberous Sclerosis Complex, and an Instructor at Harvard Medical School. He is also affiliated with the Epilepsy Genetics Program at Boston Children’s Hospital (BCH) under Dr. Ann Poduri, MD, MPH. Dr. McGraw is site PI for the Epilepsy Learning Healthcare System (ELHS) at MGH, a multi-center initiative to improve the quality of care for patients with epilepsy.

Biography

Dr. McGraw completed a combined MSTP MD/PhD program at Baylor College of Medicine (BCM) with a PhD in Developmental Biology under Dr. Huda Y. Zoghbi, MD in 2012 before completing his MD in 2014. He completed residency in Adult Neurology at University of California San Francisco (UCSF), where he received a competitive R25 award to study epilepsy in zebrafish with Dr. Scott Baraban PhD. He completed the Adult Epilepsy Fellowship at Massachusetts General Hospital (MGH) in 2020.

His research uses genetics to understand the molecular pathways underlying seizure susceptibility in rare and common epilepsies and for identifying novel therapies through genetic and pharmacological screening.

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About Us.

Dr. Chris McGraw, MD, PhD

Dr. McGraw is an Adult Epileptologist at Massachusetts General Hospital on the Epilepsy Service and the Herscot Center for Tuberous Sclerosis Complex, and an Instructor at Harvard Medical School. He is also affiliated with the Epilepsy Genetics Program at Boston Children’s Hospital (BCH) under Dr. Ann Poduri, MD, MPH. Dr. McGraw is site PI for the Epilepsy Learning Healthcare System (ELHS) at MGH, a multi-center initiative to improve the quality of care for patients with epilepsy.

Biography

Dr. McGraw completed a combined MSTP MD/PhD program at Baylor College of Medicine (BCM) with a PhD in Developmental Biology under Dr. Huda Y. Zoghbi, MD in 2012 before completing his MD in 2014. He completed residency in Adult Neurology at University of California San Francisco (UCSF), where he received a competitive R25 award to study epilepsy in zebrafish with Dr. Scott Baraban PhD. He completed the Adult Epilepsy Fellowship at Massachusetts General Hospital (MGH) in 2020.

His research uses genetics to understand the molecular pathways underlying seizure susceptibility in rare and common epilepsies and for identifying novel therapies through genetic and pharmacological screening.

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If you are interested in being part of our growing team, apply here

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cmmcgraw(@)mgh.harvard.edu

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